LGSIL/LSIL (Low Grade Squamous Intraepithelial Lesion) Treatment


Symptoms and Treatment of LGSIL or LSIL (Low Grade Squamous Intraepithelial Lesion), a type of cervical cancer. Low grade squamous intraepithelial lesion usually abbreviated as LGSIL is a kind of abnormal development of squamous cells on the surface of the cervix. LSIL is also called as mild dysplasia.

Squamous Cells are flattened, scale-like types of epithelial cells. Epithelial cells are the cells that absorb, move, and distribute some of the percentage of the fluids and nutrients in the body.

The Cervix is a small, cylindrical shaped organ that structures the lower part and neck of the uterus. The Uterus is a hollow organ in a female’s body where the egg is embedded and the fetus develops. The cervix connects the uterus and the vagina. The surface of the cervix is comprised of two distinct types of cells:

    >Squamous epithelial cells that are the lining cells of the external part of the cervix, or ectocervix)
  • Columnar epithelial cells (the covering cells of the internal part of the cervix, or endocervix)

There could be low-grade squamous intraepithelial sores and high grade squamous intraepithelial injuries. The expressions low grade and high grade in reference to Squamous Intraepithelial Lesions allude to how unusual the cells are and to what extent the cervix is affected.

A low grade squamous intraepithelial lesion or LGSIL is one in which the cells are not extremely abnormal and very little of the cervix is get affected. A high grade squamous intraepithelial lesion (generally curtailed HGSIL) is one in which the cells are extremely abnormal and a significant part of the cervix is affected.

LGSIL/LSIL (Low Grade Squamous Intraepithelial Lesion) Symptoms and Treatment

LGSIL or Low grade squamous epithelial lesions are mainly caused by infections or healing from a minor injury. Sometimes it is also considered as idiopathic (having no cause or unknown cause).

Having a low grade squamous intraepithelial lesion does not imply that malignancy is present. Cancer is an anomalous development of new tissue characterized by uncontrolled growth of abnormally structured cells that have a more primitive structure. The presence of low-grade squamous intraepithelial lesions represents changes in cells that may happen before cancer is present. Therefore, low-grade squamous intraepithelial lesions are some of the time seen by specialists as warnings that cancer of the cervix may happen at a later date.

Symptoms, Treatment of LSIL (Low Grade Squamous Intraepithelial Lesion)

LGSIL or LSIL (Low Grade Squamous Intraepithelial Lesion)

Low-grade squamous intraepithelial lesions (LGSIL) are normally diagnosed by Pap smear or colposcopy. The complete approach is to analyze a low grade squamous intraepithelial lesion is with a biopsy done during a colposcopy.


Commonly, a low-grade squamous intraepithelial lesion won’t show itself in its initial incarnation. On the other hand, as the lesion spreads, the distinctive signs and symptoms may show up.

Pruritus: Long-standing pruritus or itching and soreness are the most widely recognized beginning indications of a low-grade squamous intraepithelial lesion. Itching happens in half of the considerable number of patients with these sores.

Bleeding: Bleeding, foul smelling discharge and pain might likewise be present and are generally giveaway signs that the infection has surely advanced. There may be a few occurrences when the lesions may be noticeable and available and grow moderately gradually.

Early lesions may show up as chronic dermatitis or inflammation of the skin. Later on, some of these patients might likewise see that a protuberance or lump will then keep on developing and will in the end turn into a hard, ulcerated, and cauliflower-like in appearance.

Low Grade Squamous Intraepithelial Lesion Treatment

Once in a while, low-grade squamous intraepithelial lesions go away without treatment. The milder the condition, the more probable it will go away without treatment. A few physicians, however, may evacuate low-grade squamous intraepithelial lesions since it is possible for them to advance to cancer of the cervix.

The aftereffects of the colposcopy, and not the Pap smear, will give the premise to treatment. This is on account of a colposcopy (combined with a biopsy) is a more conclusive test than the Pap smear.

The objective of treatment is to devastate and/or uproot the anomalous cells on the cervix so that new healthy cells will become over the area where the abnormalities were present.

Squamous intraepithelial lesions can be devastated by applying below freezing temperatures to them, by utilizing lasers, or by applying heat and/or electrical currents. Treatment is divided as

  • Ablative treatment for LSIL (Low Grade Squamous Intraepithelial Lesion)
  • Excisional treatment for LSIL (Low Grade Squamous Intraepithelial Lesion)
  • Surgical treatment for LSIL (Low Grade Squamous Intraepithelial Lesion)

Ablative Treatment for LGSIL (Low Grade Squamous Intraepithelial Lesion)

Cryotherapy: An instrument is used to freeze the abnormal cells. Healing from this procedure of freezing will take around 3 weeks. A watery fluid will come from the vagina during the process of healing after applying freezing procedures. It is also known as cryosurgery.

Laser therapy: It uses focused beam of light to burn the defected cells. Destroying tissue with a laser is generally more suitable for larger areas of abnormality. Abnormal areas that enter the canal of the cervix by and large respond best to treatment with laser therapy.

Excisional Treatment for Low Grade Squamous Intraepithelial Lesion

Conization: It is done to remove the larger and cone-shaped sample of the abnormal tissue. In the event that irregular areas of tissue should be completely uprooted, a colposcopy is regularly utilized as a visual guide amid surgery. Removal of the tissue can occur during the biopsy or at a later time if the patient wishes. This procedure is also called as the cone biopsy.

Loop electrosurgical excision procedure (LEEP) is a procedure in which electric current is sent through a loop of wire to eliminate abnormal tissues. This loop acts a knife removing abnormal cells of the cervix.

Surgical Treatment for LSIL (Low Grade Squamous Intraepithelial Lesion)

Hysterectomy is a surgical procedure that is done in rare cases.

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