All about Vulvar Intraepithelial Neoplasia (VIN) Symptoms, Types and Causes.
Vulval intra-epithelial neoplasia (VIN) is a term that refers to changes that happens in the skin that covers the vulva. The vulva is the external area of female genitals. It incorporates two large, folds of skin. It is covered with hair called the labia majora, which encompass two thin and fragile folds called the labia minora. The labia majora and labia minora surrounds the opening of the vagina and the tube from which the urine is gone through (the urethra).
In Vulvar Intra-epithelial Neoplasia (VIN), the cells of the skin of part, or a few parts, of the vulva get to be anomalous and change in their appearance. It is called Vulvar Intra-epithelial Neoplasia because Vulval means affecting the vulva. Where as intraepithelial implies that the condition is constrained to inside of the skin cells (epithelium is a medical terminology for the top layer of skin). Neoplasia denotes the abnormal development, overproduction or proliferation of cells.
Despite the fact that VIN used to be entirely uncommon, it’s now being perceived and analyzed all the more frequently. It can influence ladies of any age from their 20s onwards. Vulval intraepithelial neoplasia may happen in ladies of all ages, although right now an expanded number of more youthful ladies (even youngsters) are giving the condition. The normal period of ladies with VIN is 45–50 years.
Vulvar Intraepithelial Neoplasia (VIN) Symptoms
The signs and symptoms of vulvar intraepithelial neoplasia (VIN) may change. They may incorporate some or the majority of the following:
- Itching and soreness in the vulva
- Burning or a serious tingling sensation that can turn out to be more terrible when passing urine
- One or more areas of reddened, white or discolored skin in the vulva
- Raised areas of skin that can vary in size
- The skin having a warty appearance
- Pain during sex
A few ladies indicate no symptoms and are determined to have VIN while having tests for other health issues. On the off chance that you do have any of the side effects specified here, let your specialist know. They can be caused by conditions other than VIN, however it’s best to get them checked. Your physician can look at you and, if important, refers you to a specialist who represents considerable authority in women’s health (a gynecologist).
Causes of Vulvar Intraepithelial Neoplasia (VIN)
The causes of vulvar intraepithelial neoplasia (VIN) are described below:
- Human Papilloma Virus (HPV) causes half of all instances of Vulval intraepithelial neoplasia. VIN additionally causes genital warts and other genital malignancies (cervical tumor, vaginal cancer and anal cancer). Only the oncogenic types of HPV particularly types 16 and 18 are connected with Vulval Intraepithelial Neoplasia. About half of females with VIN likewise have a background marked by anomalous cervical smears or cancers.
- Smoking is another factor associated with VIN. It is believed that the growth advancing agents in cigarettes are gathered in the skin of the lower genital tract.
- Immunosuppression by medications or infections, this reduces the body’s immunity and a female becomes more prone to it.
- Vulval Inflammation or inflammatory skin conditions, especially lichen sclerosus or erosive lichen planus
- Granuloma inguinale, a sexually transmitted ailment (STD)
Type of Vulvar Intraepithelial Neoplasia (VIN)
There are two principle vulvar intra-epithelial neoplasia (VIN) types, contingent upon its characteristics.
Usual Type VIN
Almost all VIN is usual type VIN. This type is more common in younger ladies aged 35–55 and is connected with the human papilloma virus (HPV). Common sort VIN can be further classified into:
- VIN, warty type
- VIN, basaloid type
- VIN, blended (warty, basaloid) type
The grades relates with the thickness of the surface layer of skin that is influenced by unusual cells. Up until fairly recently, usual type vulvar intra-epithelial neoplasia was categorized in not the same way. Usual type VIN was grouped differently. It was divided into 3 grades called:
- VIN type 1, implies less than 33% of the skin covering the vulva has unusual cells.
- VIN type 2, implies under 66% of the skin has abnormal cells.
- VIN type 3, implies more than 66% of the skin covering the vulva has abnormal cells.
VIN 1 (low grade VIN) is by and large a mild abnormality and most of the time goes away itself. This is no more delegated VIN as there is no clear evidence that there is a connection with it and vulval cancer. Doctors now bunch VIN 2 and 3 (high grade VIN) together to shape the usual type VIN category.
Differentiated Type VIN
This sort is much rarer. It’s more observed in older females of age 55–85 years. It can regularly happen together with other skin conditions that can affect the vulva, for example, lichen sclerosis or lichen planus.
VIN is not a cancer disease. In some of the patients it diminishes without treatment. But in the event that the progressions turn out to be more extreme, there is a chance that VIN can develop into cancer if left untreated for many years. That’s the reason Vulvar Intraepithelial Neoplasia (VIN) is considered as pre-cancerous condition.